Elimination Reactions
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  poor nucleophiles in protic solvents catalyzed by acids good nucleophiles in aprotic solvents strong bases strong sterically hindered bases
methyl very slow or no reaction SN2 SN2 SN2
primary rearrangements SN2 SN2 E2
primary hindered rearrangements SN2 E2 E2
secondary SN1, E1 with heat (Saytzeff) SN2 E2 (Saytzeff) E2 (Hofmann)
tertiary SN1, E1 with heat (Saytzeff) SN1, E1 with heat (Saytzeff) E2 (Saytzeff) E2 (Hofmann)

Elimination Reactions

 

 

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Thursday, August 05, 2010 20:18